Engine misfire why?

Takes off fine seems like goes shift in second gear has trouble starts jerking then idle rough. Replace plugs and wires new fuel pumps and filter. Still does not run right.

Sorry, it has a mis-fire that seems like a vibration as in a cylinder not firing maybe. I have a van that would sometimes kill a plug and it made a bad shaking/vibration in the motor.

I am at my wits end not knowing what else to do. Could a bad injector cause this? If so how does one check for that?

Again thank you as I know you are putting in way more time that my little $10 is worth!

I just drove it about 25 miles. When it started (started just fine) it worked great for about a mile. Going through all the gears. While it is working ok seems to me like the converter after shifting into od is running at a little higher RMP but as soon as it goes bad, (the converter seems to go into another shift or something and then it starts making the jerking motion. On the drive over it was on a scale of 1-10 say a 8 but on the way back it was noticeably worse. It makes spark knock more on the way back and has a over all miss that you can feel continuously. On any pull it spark knocks and loses speed (just a little). When I get off the interstate I have to turn off the OD or you can't hardly drive it, keeping the RPM's up helps it.