No crank no start

Okay.

Did you remember to have to key on run when testing fuse #27?
Plus you forgot to mention that "In Key" fuse in the center console fuse box.
Lastly does that crank relay 57 click once when the key it turned to start?

It appears you have a faulty ignition switch.
The "In Key" fuse is #42 in the floor console fuse box shown here.
Double check at the ignition switch the orange wire coming in for voltage from that fuse IGN 3 # 19 and with the key on run, the pink wire coming out that goes to that IGN Main 1 #27 fuse.

Are you listening to the radio or something while doing all this testing?

The orange wire coming in for voltage from that fuse IGN 3 # 19 and with the key on run.
Are you sure you had the key on run?
If yes, and you are sure both sides of that IGN 3 #19 fuse has 12 volts on both sides then you have an open or short in that orange wire and maybe not a faulty ignition switch. Trace that orange wire and find the open, short or cut both ends and run a new wire, tape up the ends of the old wire, Then see if all is okay, now, then move onto finding out why the battery drains so fast.

What hot wire?
Was it that orange wire?
Plus, why do you have the running lights on when doing these tests?

You may have to gain access to that #19 fuse socket by either taking the fuse box apart or taking it off, whatever it takes to find out which orange wire it is. You may want to disconnect the battery just for now while you gain that access just so you don't short out something else, then hook it back up when you have identified that orange wire and are ready to begin testing it for where it looses that voltage at, whether it be a short circuit, short to ground or open (break) in the orange wire.

It appears now the security system has a problem reading the key password. Maybe the fact the battery kept going dead, it lost the memory. For now, try a spare key if you have one or if you don't try cleaning that key where the pellet is and try again. Last try to relearn the password, but you should keep the battery charger on the battery while doing so, cause you have to leave the key on for 30 minutes. So make sure you also turn everything off, including those running lights. Put the key in the ignition, turn the key to run, wait 10 minutes and see if the security light goes out. If and when it does, turn off the key, turn the key back to run and leave it there for 10 minutes, turn it off again. Turn it back to run for another 10 minutes, for 30 minutes total, then turn it off, now this time turn the key to start, the security system should learn the password this time and crank the starter and engine over and see if it starts and runs. If not, you will have to have the trouble codes retrieved to find out what on that security system is at fault. Plus is when turning the key to run, for that first time if the security light never goes out after 10 minutes, you will probably have to retrieve the trouble codes anyhow.