It is possible for all the ignition coils to go out at the same time. I had the exact same problem on a 2001 F150 right at about 100K miles on the engine. I ended up replacing all the coils, spark plugs, O2 sensors, new O-ring kits on the fuel injectors and new catalytic convertors. It was alot of money to drop all at once but worth it as I don't have any ignition problems anymore and I'm now at 146K miles.
I'm not suggesting that you have to do all this work, I just wanted to do a comprehensive tune up to my own truck.
Hope this helps
rjr1
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Monday, October 6th, 2008 AT 2:28 AM