Engine bogs and will not accelerate?

Fuel pressure is 42 psi.
Vacuum tested - steady @ 19hg when revved drops slightly then climbs to 24hg.
Ran w/o muffler and no change cat is new replaced because old one was gutted causing o2 sensors to have identical reading which causes improper fuel mixture.

Have a 97 chevy s10. Replaced plugs, wires, cat, muffler, and o2 sensor (after cat). Have a problem when driving on the highway in fifth gear. When I have it in fifth it has no power I start to drop in speed when I put the pedal down harder it feels like it could be flooding up. I have to drop it back into fourth gear to get any power and speed up. I get nothing out of fifth gear. What could cause this. It has a rough idle as well. 1997 chevy s10 ls 2.2L

Fuel pressure is between 41 and 47 psi

When I am driving down the freeway at about 60mph my car starts to have a little vibration on floorboard and a somewhat loud noise to it and my floor board heats up what could the problem be. Ive already had my transmisson serviced and nothing seemed to be the problem and I have spent 1600$ dollars on fixing it since ive bought in in october of 2009. And also when I drive it boggs out when it wants to and then shuts off and I cant seem to find the problem.

Both floorboards get hot but mostly driver side.

=, mechanic001]
both floorboards get hot but mostly driver side. And my car is getting worse at dying and bogging out

Also, the CAT convert has been out for 3 or so years and engine worked fine up to this point. I also had it scan before changing all the parts listed and they were: PO121, PO122, PO171, PO172, PO300, PO404, PO405, PO420 and PI1404, that's why I started changing out parts.

I'll check the fuel pressure and as far as I can tell all the vacuum lines are okay but one thing that I am concerned about is the TBS area behind the TBS is an open space to the left side that I noticed after installing the new one. I checked the manaual and nothing is noted. Is there suppose to be a gasket to cover that open area or is that just the way it is? I did not check it before I removed it but it came off as one piece. Thanks for your help!

Sorry for the delay to respond back but I had a mechanic check the engine out and he found lifter's on cylinder 1 were bad so he replace all lifters. The engine ran but it kept idleing off. He checked the pcm and it showed tps, he cleared the codes and tested it again and the tps showed up again. He unpluged the tps and it ran okay. I had installed a new tps before the engine work. I took the new-old one back and replaced it with a new AC Delco model and the engine runs good but at times some hesitation. I know the engine has over 200,000 miles but it just don't have the power it had before things started going wrong while still in the high milage numbers. When driving down the interstate at 65 now and I come up on an incline the truck slows down instead of keeping the speed. I also still hear more vacume noise from the engine when accelarating than when all my engine problems started. There has to be something that I've missed or am not aware of that can fix this problem. Any thoughts will help. I'm also thinking that instead of a vacume leak that one of the vacume lines might be clogged. I cleaned the air pliemun and used carburator clean at the vacume ports on top of the air pliemum. I did not disconnect the lines thou. I did install a new set of fuel injectors and gas requlator. I finished filling the tank up with new gas, 14 gallons to a 18 gallon tank. The mechanic did not think it was the gas pump so that has not been changed. I can go on and on but I'm searching for an answer with out having to pay another arm and leg for a almost complete repair, thanks again and just maybe you have the answer or someone you know might have had this same problem and has the solution. Thanks again for your time and help!