Hi and welcome back.
A dead miss is when one or more of the cylinders begin to misfire all the time and not at random times. Is the only code you get the random misfire (P0300)? As far as the cam, I honestly do not think it would cause a dead miss. Even though it is beyond what is considered tolerance, I feel it would miss all the time if the cam was the issue.
Next, have you confirmed that fuel pressure is within the manufacturer's specs? Weak pressure can cause a random misfire.
https://www.2carpros.com/articles/how-to-check-fuel-system-pressure-and-regulator
As far as the camshaft, a re-builder would replace it because it exceeds the maximum that is considered acceptable. Also, unless the air filter it plugged, it should not be the cause unless it is really bad.
Focus on the things that both Ken and I suggested. Let us know what you find. One last thought. With 275,000 miles on the vehicle, you have to keep in mind that engine compression it self could be an issue.
Let us know what you find.
Joe
Tuesday, October 16th, 2018 AT 5:38 PM