Hi,
The code 45 is likely the result of the 22. As far as the TPS, it is on the throttle body and can be replaced. However, before you replace it, take a look through the diagnostic flow chart I attached below. (pic 1) It will help determine if it is bad or if there is a wiring issue. The code indicates low voltage, so chances are it is a loose connection, corroded connection, shorted wire and so on.
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If you decide to replace it, here are the directions. Pic 2 correlates with these directions.
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1990 Chevy Truck C 1500 Truck 2WD V8-350 5.7L
Throttle Position Sensor (TPS) Replacement
Vehicle Powertrain Management Fuel Delivery and Air Induction Sensors and Switches - Fuel Delivery and Air Induction Throttle Position Sensor Service and Repair Procedures Throttle Position Sensor (TPS) Replacement
THROTTLE POSITION SENSOR (TPS) REPLACEMENT
Throttle Position (TP) Sensor
Pic 2
REMOVAL:
1. Disconnect electrical connectors.
2. Remove the TPS attaching screw assemblies and retainer, (if applicable).
3. Remove TPS from throttle body assembly.
NOTE: The TPS is an electrical component and must not be soaked in any liquid cleaner or solvent, as damage may result.
INSTALLATION:
1. Install TPS to throttle body assembly, while lining up TPS lever with TPS drive lever on throttle body.
2. Install the two attaching screw assemblies. Tighten screw assemblies to 2.0 Nm (18.0 lb-in).
3. Install electrical connector to TPS.
4. Check for TPS output as follows:
a. Connect an ALDL scanner to read TPS output voltage.
b. With ignition ON and engine stopped, TPS voltage should be less than 1.25 volts. If more than 1.25 volts, replace TPS.
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You asked about the catalytic converter. If it is plugging, you will certainly experience issues, especially a loss of power. Also, if you hear rattling in the exhaust, there is a good chance it came apart internally. Here is a link you may find of interest. It discusses common symptoms related to a bad converter.
https://www.2carpros.com/articles/bad-catalytic-converter-symptoms
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I hope something here helps. Let me know what you find or if you have other questions.
Take care,
Joe
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Tuesday, October 13th, 2020 AT 6:21 PM