The engine cranks but will not start unless spark plugs are removed?

Sounds like the classic blown head gasket. check the compression in those 2 cylinders to see they could be leaking between them.

Did it over heat before this ? Any codes or check engine light on the dash ?

No. I did compression check. number 3 is at 130 PSI all others are 185 psi. Would this indicate head gasket?

Probably not blown but not sure yet take the cap off and check the radiator see if theres any milky Sludge in the filler neck
Also check the oil for the same Sludge on the stick if theyre clean let me know also it would be great if you could post a photo here ..let me know thanks good luck

There are a few things that can cause this problem we can work to rule them out ..is it possible someone crossed the coil plugs on numbers 2 and 3 ?

Also when is the last time it was running well ?
Was any work performed since then ?

You truck came with 2 different coil types
1..coil on plug type (each plug gets its own coil )
And
2..coil pack ( a block wich all 6 wires plug into )

Wich type does yours have ? Description 1 or 2.. ?