Radio powers on but no sound

Looking at the wiring diagrams it appears that car only has the audio output in the head unit and no external amplifier. That suggests it is something internal to the unit that failed. To be sure you could test the speakers but it's doubtful that they would all fail at the same time. What is more likely is that the power feed to the amplifier chip in the unit has failed.
As you know how to remove it already you also know how it is replaced. However replacement is a pain because of the way Honda has the security system in those cars. Replacement of the unit itself simple, the trick is in having the replacement unit programmed so that the security system doesn't lock it up. For that you really need a dealership as you need access to Honda's online system to reset the security section of the audio unit.

Hello,

Sounds like you could have an issue with the factory amp or it could be grounded out wire on one of the speakers.
This car comes with "Smart amp", Which can monitor the output to the speakers. And if one of the speaker goes out it can cut power to all of them.
Try disconnecting one speaker at a time to see if the sound comes back on. That way you will know the faulty one.

https://www.2carpros.com/articles/how-to-check-wiring

I have also included the wiring diagram for your reference.

Please let me know of any questions.

Thank you.