Thanks,
Jgraff
Confirm actual spark from the waste-spark coils (cylinders 1 and 3 share one coil; 2 and 4 share the other), since a dead coil can wet both paired plugs. Recheck compression on cylinders 3 and 4 and inspect the head gasket closely between them. Check for vacuum leaks and broken lines. Before reinstalling the head, verify it is flat, use new head bolts, and watch the driver-side rear corner for coolant leaks common on 2.2L heads.
A 1999 Chevy S-10 2.2L developed a strong miss and white smoke with black soot. Cylinders 3 and 4 were not firing; fuel pressure was about 41 psi, the scan showed no faults, and replacing those injectors did not help. The plugs were very wet, but the head, valves, pistons, and rings looked fine. An expert advised verifying spark on the paired coils, rechecking compression, inspecting the gasket between those cylinders, checking vacuum leaks, confirming the head is flat, installing new head bolts, and watching for a coolant leak at the driver-side rear corner. A second owner reported a similar rich, smoky condition on a 1997 Sonoma 2.2L, with no separate diagnosis given.