Car hesitates when accelerating, check engine light turns on and code P0300

My car isn’t popping any codes except for P0300. I checked my ignition and fuel systems and they check out but my car stills hesitates when accelerating, it even sputters while idling and shakes the whole car. When idling like that I noticed the exhaust pipe was vibrating violently. And when I came back from the test drive it even shut off completely. It does this more than it you to when it only did it while the car was warmed up. It has something to do with temperature. I changed the o2 sensors, the fuel filter, the coil wires, MAP sensor, crank/camshaft position sensor. I even scanned it for codes. No codes. I'm at a loss here. I have no more ideas or patience to keep guessing the part that is causing this. There's no vacuum leak. One thing it does if I push it hard is that the Check engine Light comes on to tell pop the p0300 code.
Please help I am at my wits end.