Replacing the ignition and door lock cylinders?

I'd like to replace the lock cylinders on the truck listed above Silverado but saw something on Amazon that made me think it somehow matters if I have a manual transmission and not an automatic when buying the lock cylinder set (ignition and door locks). Does it really matter? I had just done this on my 1999 Corolla and did not come across anything about which transmission I had making any difference. I had to ask before I just take a chance.