2000 Chevy Blazer Engine Failure

With that miloage, a number of things. Where are you on routine maintanence? Has ou had a loss of power before this started? Look for vacuum leaks and check fuel pressure (can rent guage from advanced) for lack of power, and possible problem see. Engine lacks power. See one of the following: 1.) Incorrect ignition timing. 2) Fuel filter clogged and/of impurities in fuel 3) Faulty or incorrect gapped spark plugs. 4) Air filter dirty. 5) Spark timing control system not working properly. 6) Faulty ignition coil(s) 7) Brakes binding. 8) Auto Trans fluid not correct 9) faulty distributor cap or wires 10) EGR system not functioning properly. 11) Use of sub standard fuel. 12) Low or uneven cylinder compression pressures 13) Air vacuum leak at intake manifold or plenum