Bank A misfires, codes: P0345, P0300, P0302, P0304 and P0306

I appreciate the reply and thank you for the Diagram/Schematics as it is not easy to find them online. I will most certainly let you know what I can find... I suspect the ECU if that is what you meant by PCM. Upon further testing yesterday(Sunday)... It seems that both Cam/VVT sensors along with Crank Sensor are directly connected to the ECU without any breaks prior to ECU. There is a junction somewhere for the ground connections but grounds look solid based on various continuity checks.

Apologies for the delay.
I have performed many continuity checks between both cam sensors and the crank shaft sensor. The diagram attached shows where there is no signal. There seems to be no shorts or breaks with all three sensors and no visible water damage of any kind.

First I need to say that I had found a workshop manual for a 2001 Avalon online( have to sift through it a page at a time no link able index) which gives a few more details as to the resistances (hot and cold) that should appear at all three sensors and what the signal/voltage range is with all sensors.

It turns out that the cam sensors sold to me by O'Reily auto parts do not meet the resistance ranges that are mentioned in the manual(around 1,000 cold) and have the resistance range of the crankshaft sensor(around 2,000 cold). However I have one of the original cam sensors and its resistance range is in the 1,000 range. The workshop manual states to replace the sensors if the ranges are not within the appropriate values..I will need to get Denso replacements.

As stated, I have performed many continuity checks with the determination that there is no signal at e4 pin 22 of the ECU since there is a 24,000 resistance value from pin 22 of connector e4 and pin 25 of connector e5, it has been determined that the connection is solid through to the ECU board itself(internally, there is a 24,000 resistor that is across the two connections. I have traced the circuit for both sensors to an IC that has no distinguishable number).

There is signal at the other two sensors (cam and crank sensor)... The ne- at pin 25 is labeled as e2 ground in the service manual-not case ground. There is a 100ohms between e2 and case/body ground so there is some form of power inversion within the ecu to create AC based frequency signals.

I am still looking for any parts(resistors/capacitors etc) that may be blown within the ecu but so far all resistors that I can trace test okay. Caps are a little harder to check when in circuit. The board itself is multilayered(more than two layers of pathways) which makes things difficult to reverse engineer without a schematic of the ECU itself.

Is there any other area that may have influence on whether the sensor in question actually has signal?

If the ECU is bad where can I get another cheaply because Toyota wants way too much money for a replacement?

If the ECU needs replacement, what are the instructions to reset the keys? I have heard of shorting 2 pins on the scanner port.

The site mentioned above does not have computers for a 2003 Toyota Avalon.
Do you know of any other reputable places?

After replacing the Cam Position sensors with Denso parts, trying to find an ECU, being sent a bad ECU by store. Allcomputerresources which seem to be scammers, and replacing the VVT associated with the left side of the engine with no change. The car was taken to an Auto Shop that specializes in Electrical issues.

The Auto Shop could not find the issue electrically and had to take the top of the engine off and stated that the Camshaft cracked the center cylinder(#2). This is a second hand description by my wife who dealt with the Auto Shop. The car did not have regular oil changes prior to my wife owning the car.

According to the Auto Shop the car needs a new engine.