This photo is for a 2008 model 2500. It appears the left and right shafts are the same part number. Once the truck is safely supported on jack stands under the frame rails, it's okay to loosen the axle nut. Don't do that at any time when there's vehicle weight on the tires as that will instantly make that wheel bearing noisy. If the nut is a castle nut with a cotter pin, it can be reused. (Blue arrow). If it's a lock nut, those are a "torque to yield" nut which is a one-time-use nut. A new one must be used each time. The torque value is 177 foot-pounds and is critical. Use a click-type torque wrench.
Disconnect the lower ball joint, then pry the lower control arm down and pull the spindle away from the outer CV joint. It will be easier if you turn the steering system to one side.
Check the two mating surfaces at the red arrow for dirt or debris, then install the new shaft.
To answer your question about needing an alignment, you will not because nothing you're taking apart has anything to do with holding the wheel in alignment. You would need an alignment if a coil spring or any control arm was replaced.
You can find replacements at any auto parts store. It's hard to find rebuilt shafts because new ones are so inexpensive today. Rock Auto is a popular online site too.
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Saturday, February 26th, 2022 AT 4:06 PM