Lexus es300

While driving my car began to sputter. The check fuel light (not the low fuel indicator) came on and then followed the taction control light. My wife had fuel the car up prior to our trip so it had a full tank of gas. I went to autozone and they suggested I add some fuel addative so I did and the car continued to sputter. I had a code scan performed and it stated had a random cylinder misfire. It also showed to have a misfire on cylinder 3 and 4 codes were P0300, P0304 and P0303. Probable causes were: vacuum leak, fuel system concern, ignition system concern, and engine mechanical condition. I checked for a vacuum leak but could not hear anything loud. I checked the 3 front spark plugs one was golden, one was black and one was a little white. I didnt do the back spark plugs yet because I didnt want to remove the intake just yet. The previous owner provided a receipt showing replace coil #2 due to a coil pack malfunction code P0302. Could this be the same problem I am now having? The car has 95000 miles on it. Thank You David