A 2000 Escalade should not have throttle body injection, ( although it does have a throttle body)
It should have one injector per cylinder located below the upper intake manifold along with the fuel pressure regulator.
On these engines faulty injectors were quite common, unfortunately you cannot see them without removing the upper intake manifold to expose what is called the spider.
If you know someone with a snap on scanner, you can perform an injector balance test to see if the injector is working properly. If not you may just have to take a chance and replace the injector.
You can also try a good injector cleaning, this may help depending on how bad shape it is in.
Hope this helps!
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Monday, March 10th, 2008 AT 6:40 AM