Misfire not enough fuel or water in gas?

I've Experienced a on and off Scenario mostly doing it now. It was a cold wet day and started up and ran fine went to Walmart and then started to go home and halfway if started like misfiring/cutting fuel/falling on its face with the whole motor jumping. About 50-55 it did it, so I babied it home then it got really bad and unhappy. Parked it then changed the TPS sensor on 3 days later on a dry day and ran drove and floored it and she was happy. Then we had some cold freezing nights some snow. Then I started it up got some 87 gas, then started it and then the something is happening again. I go grab Heet and octane booster and she liked that. She was fine then started it after some snow Filled up like 4 days later and parked it. Then we got some good snow that night with freezing rain l started it next day and man she was running ruff 3 to 4, 5 Cylinder is firing got more Heet and tried to clear it out later that day filled all the way up with 97 at a different gas station with octane booster and additives. She cleaned out that night and ran fine after driving it for a minute. Parked it then got rain and snow for 3 days then started it and same thing. Is water in the gas? Is it another bad TPS? Maybe a bad crank or cam sensor? Or spark

The vehicle listed above has a 4.3 tbi.